At home: PROs - more flexibility in work hours and you can get other things done during down time, no commute time or expense, potentially more solitude, less overhead expense if you are self employed

CONs - possibly more distractions, especially if you have kids or a spouse or roommate and neighbors and friends may interrupt more or expect you to be more available for personal issues; less interaction with peers and coworkers; need to be vigilant that work tasks do not creep into personal time; need to be really self-motivated and self-disciplined

the only way you will be able to work from home is if you have your own business that can be run from home