You can learn about one of the bigger successes, theMountain.com, which sell the 3D look animal prints.
In an Interviewed - Capacity 100.000 a week, 230+ employees
http://video.foxnews.com/v/2368841977001...
Alternate schemes for testing te waters, include the print on demand sites that allow you to setup a 'store' showing your designs, including CafePress.com, Zazzle.com, Customink.com, I have heard people don't make a lot of sales, perhaps becasue these sites have Millions of seller pages.
There are several paid courses out on making money through TeeSpring.com, a sort of crowd funding site for limited edition designs targeting a very specific demographic like Gun or Pitbull lovers. Nobody pays until your quota of 10 or more pieces is reached, it requires no funds on your part. The courses generally talk about using Facebook's demographic targeted paid ads or a popular FB page.
Does anyone make any money from selling shirts online, like simple corny ones or meme based ones and such? i was looking to get some insight from the average seller, you dont have to be making thousands or hundreds of dollars, just anything.