Normally, when people complain about their boss singling them out, it is generally not the boss who is the problem. In your case, however, this sounds very different. If it's reached the point where your co-workers are not just noticing the unfair treatment, but joking about it and telling you that they notice, it must be pretty bad. They wouldn't notice if it was just occasional, nor would they say anything about it if they didn't realize it was unfair. If you were just a crappy worker, they wouldn't mind it at all. Obviously, your boss has a problem with you, and I would talk to her to find out what it is. If this environment doesn't change, its time to transfer or find a new company, because this is the negative type of stress that destroys your health over time.
if your boss' boss has an open door policy, you should discuss it with him/her. be sure to keep written notes of when these reprimands take place and what you did to correct them so you can annotate them in your annual review. It sounds like your boss' review of you will not be favorable. Be ready to counter any points she may have about you. When you sit down for the one-on-one, be sure to request her boss' presence as well so it will be witnessed.
If you you do not get a favorable review, if it is deserved of course, then consider looking for another job and be sure to let your boss' boss know this is why you are leaving.
this boss is not going to change. accept this. there are 'bosses' out there who are severely demented but get away with a lot. move on. even asking her what her problem is won't cut it, because she's "perfect" and you are not worth her time and for this she is rewarded. you will need to switch companies.
Managers expect more of efficient staff and are tougher on them. This unfair I know but it's a compliment. Have a chat with your boss and tell her that her attitude upsets you.
What you do is try your best to improve whatever behavior she's correcting you on. The number of employees who think they're being singled out unfairly by a supervisor far exceeds the number of employees who are actually being singled out unfairly by a supervisor. You should consider the possibility that her criticism is warranted.
Put in for a transfer. Begin documenting her behavior in detail and hand it over to HR when you put in for your transfer. If you can't do that, start looking for a new job.
Figure out what it is that your doing differently from your peers that she seems to like so much. Otherwise, endure it and do your job until you have a different job.
Ask her specifics. If she won't deal with you directly, you want yo change jobs. She seems hard to please.
If you are the only one being treated that way then one can surmise the problem is you
She may have a crush on you.